What has the MTHFR C677T gene got to do with overall methylation?

Sometimes we can get bogged down with gene testing, but it is important to know that methylation is the result of a huge process within which many genes are responsible.

It is the OVERALL NET METHYLATION outcome of the hundreds of methylation pathways in the body, that really depict what is going to show up clinically and behaviourally, in a person.

Can you be MTHFR C677T and A1298C homozyous/compound heterozygous and be an overmethylator?

Technically yes, as there are many other gene SNPs which also add to the equation.

How will you know your net methylation status?

A thorough clinical history and examination, with minimal functional testing and interpretation by an experienced functional medicine practitioner.

Methylation is a biochemical process responsible for dozens of chemical reactions in the body and the brain. Not only is it essential to physical and mental health, but also influences an individual's characteristics and traits.

For example, undermethylation is associated with perfectionism, high accomplishment, OCD tendencies, and seasonal allergies.